Hypoglycemic potential of genus Ficus L.: A review of ten years of plant based medicine used to cure diabetes (2000-2010). Khan KY, Khan MA, Ahmad M, Hussain I, Mazari P, Fazal H, et al. Isolasi dan Sitotoksisitas Ektrak Flavonoid daun Tin (Ficus carica L). The efficacy and safety study of dietary supplement PURIAM110 on non-insulin taking Korean adults in the stage of pre-diabetes and diabetes mellitus: Protocol for a randomized, double-blind, CMC Na-controlled, and multicenter trial-pilot study. Park S, Park JS, Go H, Jang BH, Shin Y, Ko SG. Brussels, Belgium: International Diabetes Federation 2015. When it was compared to the positive group, it had significant results with a statistical value (p < 0.05).Д¬ONCLUSION: Ethanol extract of fig leaf tablets had a significant effect on lowering ratsвЂ™ blood glucose levels. The treatment group of the ethanol extract of fig leaves at a dose of 40 mg, ethanol extract of fig leaves at a dose of 60 mg, and ethanol extract of fig leaves at a dose of 80 mg could reduce ratsвЂ™ blood glucose levels with statistically significant results (p < 0.05) compared to negative group. Whereas the dissolution rate (DE45) of each formulation decreased with increasing dose of extract, FI (73.73%), FII (74.80%), and FIII (69.80%). As for the uniformity of size, all formulas have a diameter of 0.9 В± 0.0 (cm).

While the disintegration time of FI (11.02 min), FII (10.10 min), and FIII (17.00 min), placebo tablet (12.23%).

For the hardness values of FI (5.7 kg), FII (1.31 kg), and FIII (3.09 kg), placebo tablet (2.98%).

After giving treatment to each group for 14 days, a rat blood sample was then taken on days 9 and 14, which were then analyzed by the GOD PAP method with readings carried out using a spectrophotometer with a wavelength of 500 nm. Previously, rats were induced first using alloxan 150 mg/kg intraperitoneally to damage ОІ-pancreatic cells so that the rats could experience increased blood glucose levels. The antidiabetic activity was evaluated from a decrease in rat blood glucose levels. There were eight groups of male rats strain Wistar treated as follows: Normal control, negative control, positive control (metformin tablets), basis group, placebo treatment group, F1, F2, and F3 groups. Formula I (FI), Formula I (FII), and Formula III (FIII) groups to give a tablet of ethanol extract of fig leaves with a dose of 40 mg, 60 mg, and 80 mg and placebo treatment group. METHODS: Four tablet formulas were made using the wet granulation method. However, the use of fresh leaves makes the effects obtained is not measurable and efficient.ДЄIM: The purpose of this research was to determine the antidiabetic potential of ethanol extract of fig leaves and to optimize tablet dosage formulations. Department of Pharmacy Technology, School of Pharmacy, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Yogyakarta, IndonesiaДЇig leaves, Antidiabetic, Tablet AbstractД«ACKGROUND: Fig leaves are reported to have an effect on reducing blood glucose levels.

Figleaf of beta